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Representative Precision Medicine Research Through Partnerships

Grantor:
CA Health and Human Services Agency
Portal ID:
151608
Status:
Active
Opportunity Type:
  • Grant
Last Updated:
 | 
Categories:

Details

Purpose:

This funding opportunity aims to support precision medicine and representative research that leverage partnerships within California, include underrepresented populations, who have been underrecognized or historically excluded, as research participants, and reduce health disparities, so that research benefits all people within California and promotes health innovation for all California communities.  

 

Description:

Award selection will have three stages.

Deadlines:

Letter of Intent (required):  11/21/25

Initial Application:   1/23/26

Full Application:  4/24/26

The California Initiative to Advance Precision Medicine (CIAPM) will award $6 million to support approximately 3-5 project teams conducting representative precision medicine research projects in California over a 2.5-year project term. Precision medicine calls for the modern application of scientific data and clinical practice toward the individualization of prevention, diagnosis, measurement, and treatment of disease and wellbeing. This funding opportunity aims to support precision medicine and representative research that leverage partnerships within California, include underrepresented populations, who have been underrecognized or historically excluded, as research participants, and reduce health disparities, so that research benefits all people within California and promotes health innovation for all California communities. 

Research teams must be co-led by at least one California non-profit academic research institution and either (1) at least one nonprofit community-based organization, patient advocacy group, community clinic, or public or Tribal entity that adds lived experience, expertise, and/or community or data assets OR (2) another California non-profit academic research institution that adds capacity, expertise, capability, scalability, and/or training opportunities. Partnerships should aim to break down silos between academic institutions and communities (academic-community partnerships) or between academic institutions (academic-academic partnerships), connect different areas and methods of analyses within precision medicine (such as cellular and biological systems as well as community, population, and societal systems), and foster co-learning in which partners’ strengths and capacity needs are acknowledged for meaningful integration of perspectives.

Research projects must aim to make biomedical research more inclusive, and thus more applicable and beneficial to all Californians. The applicant must describe how their application will support representative research, incorporate a precision medicine approach to study health disparities, potentially including social determinants of health data, and leverage partnerships. Projects must take place in California, and data should focus on people that live in California but are not limited to only California populations. Projects must demonstrate prioritization of recruiting, enrolling, and retaining participants who are from underrepresented populations. 

The proposed research must include a deliverable of a precision medicine asset, such as a new dataset, previous datasets that have been integrated and/or optimized for interoperability, new methodology, services, resources, or a database for patients or interested research participants. The proposed research must also include the creation of promotional materials that encourage participation of individuals from underrepresented populations in the research study and that describe the importance of biomedical research in the context of the research question and populations engaged. 

Eligibility Requirements

Eligible Applicants:

  • Nonprofit
  • Public Agency
  • Tribal Government

Research teams must be co-led by at least one California non-profit academic research institution and either (1) at least one nonprofit community-based organization, patient advocacy group, community clinic, or public or Tribal entity that adds lived experience, expertise, and/or community or data assets OR (2) another California non-profit academic research institution that adds capacity, expertise, capability, scalability, and/or training opportunities.

Eligible Geographies:

Projects must take place in California, and data should focus on people that live in California but are not limited to only California populations.  

Selection considerations may include project location to balance geographic and institutional diversity of awarded primary and partner organizations, and if at least one partner is located in an area that has not recently received significant investment in federal biomedical research funding.

Matching Funding Requirement:

Additional matching funds and in-kind contributions are not required but are highly encouraged and will be considered during the selection process.

Important Dates

The date (and time, where applicable) by which all applications must be submitted to the grantmaker. Time listed as “00:00” equates to midnight.
The date on which the grantor expects to announce the recipient(s) of the grant.
May 2026
The length of time during which the grant money must be utilized.
2.5 years

Funding Details

The total projected dollar amount of the grant.
$6,000,000
A single grant opportunity may represent one or many awards. Some grantors may know in advance the exact number of awards to be given. Others may indicate a range. Some may wish to and wait until the application period closes before determining how many awards to offer; in this case, a value of “Dependent” will display.
3 – 5
Grant opportunities representing multiple awards may offer awards in the same amount or in varied amounts. Some may wish to wait until the application period closes before determining per-award amounts; in this case, a value of “Dependent” will display.
$1,200,000 – $2,000,000
Certain grants require that the recipient(s) provide a letter of intent.
Yes ( see Description for details )
Certain grants require that the recipient(s) be able to fully or partially match the grant award amount with another funding source.
No
The funding source allocated to fund the grant. It may be either State or Federal (or a combination of both), and be tied to a specific piece of legislation, a proposition, or a bond number.
  • State
The manner in which the grant funding will be delivered to the awardee. Funding methods include reimbursements (where the recipient spends out-of-pocket and is reimbursed by the grantor) and advances (where the recipient spends received grant funds directly).
  • Reimbursement(s)

Funding Method Notes:

Funds will be disbursed monthly by reimbursement. 

How to Apply

State agencies/departments recommend you read the full grant guidelines before applying.

Resources

For questions about this grant, contact:
California Initiative to Advance Precision Medicine, 1-916-279-6335, ciapm@chhs.ca.gov

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